The comedy-drama starred the late Robin Williams as a struggling actor who disguises himself as a feminine housekeeper to spend time together with his kids after he loses custody in a bitter divorce.

Speaking to Entertainment Weekly on Friday, Columbus mentioned that whereas there is no NC-17-rated version of the movie — rated PG-13 on launch — there are three totally different variations of it.

Columbus recalled doing “anywhere between 15 to 22 takes.”

“He (Williams) would sometimes go into territory that wouldn’t be appropriate for a PG-13 movie, but certainly appropriate and hilariously funny for an R-rated film.”

While some followers is likely to be delighted by the thought of an R-rated “Mrs Doubtfire,” Columbus mentioned that version of the movie will most likely by no means be launched.

“I would be open to maybe doing a documentary about the making of the film and enabling people to see certain scenes re-edited in an R-rated version,” Columbus mentioned. “I think that would be the best approach.

“Mrs Doubtfire”, which also stars Sally Field, Pierce Brosnan and Harvey Fierstein, has earned $441.3 million at the worldwide box office.

Columbus said he remains “very proud” of the movie and doesn’t wish to spoil its legacy in any way.

“I’m in a superb place with ‘Mrs. Doubtfire,’ so there’s actually no motive to do the definitive minimize. The definitive minimize of ‘Mrs. Doubtfire’ is out in the world proper now.”

Williams, widely considered one of the greatest comedic actors of his generation, first made audiences laugh on the comedy circuit and “The Richard Pryor Show,” before winning hearts across the globe as the alien Mork in TV sitcom “Mork and Mindy.”

He brought his zany energy to films such as “Dead Poets Society” and “Good Morning, Vietnam,” winning numerous awards for critically acclaimed performances, including the best supporting actor Oscar for his role as the sympathetic psychologist Sean Maguire in 1997 drama “Good Will Hunting.”

Williams died in August 2014 at the age of 63.